The Owensboro Sportscenter, home of the Kentucky Wesleyan Panthers men's and women's basketball teams, is the largest arena in the Great Midwest Athletic Conference and the 15th largest in the nation (NCAA Division II), with a seating capacity of 5,002. The Sportscenter hosts concerts, sporting events, trade shows, conventions, meetings, and receptions.

Kentucky Wesleyan opened its playing career in the Sportscenter on February 26, 1951 before a full house against Centre College. The Panthers won 114-71. Nearly 20 NCAA regional championships have been staged at the Owensboro Sportscenter. Wesleyan annually ranks among the nation's top 10 teams in attendance.

Built in 1949, this historic facility hosts concerts, sporting events, trade shows, conventions, meetings, and receptions. The Sportscenter is the home of the 8-time Division II national champions Kentucky Wesleyan Panthers basketball team. The Men's and Women's teams play in the G-MAC Conference. The Sportscenter is also home to the Owensboro Catholic High School Aces boy's and girls' basketball teams.